Museum of the Southwest Share: Museums Museum of the Southwest Visit Website 1705 W. Missouri Midland, TX 79701 (432) 683-2882 (432) 684-9151 (fax) Facebook Pinterest Instagram Hours: Open Tuesday through Saturday, 10 am to 5 pmSunday, 2 to 5 pm Closed Monday About Map About The Museum of the Southwest inspires discovery, interaction and exploration of art, science, culture and history, enriching the lives of people of all ages. What's Nearby? Distance: 5 10 15 20 25 50 mi.